Abstract In the present work, the stopping powers of alpha particle energies from near threshold energy to 10 MeV for light elements (37Li, 511B, 613C, 818O, 919F, 1022Ne, 1123Na, 1430Si) and medium elements (2145Sc, 2452Cr, 2657Fe, 2862Ni) have been calculated using the Zeigler formula. The cross-sections of the nuclear reactions 37Li(a,n)510B, 511B(a,n)714N, 613C(a,n)816O, 818O(a,n)1021Ne, 919F(a,n)1122Na, 1022Ne(a,n)1225Mg, 1123Na(a,n)1326Al, 1430Si(a,n)1633S, 2145Sc(a,n)2348V, 2452Cr(a,n)2655Fe, 2657Fe(a,n)2860Ni, 2862Ni(a,n)3065Zn have been calculated from those of the inverse nuclear reactions such as 510B(n,a)37Li, 714N(n,a)511B, 816O(n,a)613C, 1021Ne(n,a)818O, 1122Na(n,a)919F, 1225Mg(n,a)1022Ne, 1326Al(n,a)1123Na, 1633S(n,a)1430Si, 2348V(n,a)2145Sc, 2655Fe(n,a)2452Cr, 2860Ni(n,a)2657Fe, 3065Zn(n,a)2862Ni using